Publicaties Allergienetwerk studiecentrum

Allergische rhinitis

• Safety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32. (Niederberger et al, J. Allergy Clin Immunol, 2018)
• Probiotics-impregnated bedding covers for house dust mite allergic rhinitis: A pilot randomized clinical trial. (Berings M, et al, Clin Exp Allergy. 2017)
• A randomized, 5-arm dose finding study with a mite allergoid SCIT in allergic rhinoconjunctivitis patients. (Phaar O et al, Allergy. 2016)
• Allergy immunotherapy with a hypoallergenic recombinant birch pollen allergen rBet v 1-FV in a randomized controlled trial. (Klimek L, et al, Clin Transl Allergy. 2015)
• Effectiveness of MP29-02 for the treatment of allergic rhinitis in real-life: results from a noninterventional study. (Klimek L, et al, Allergy Asthma Proc. 2015)
• 300IR 5-Grass pollen sublingual tablet offers relief from nasal symptoms in patients with allergic rhinitis. (Serrano E,et al, Am J Rhinol Allergy. 2014)
• A novel intranasal therapy of azelastine with fluticasone for the treatment of allergic rhinitis.(Carr W, et al, JACI 2012)
• Efficacy of desloratadine in persistent allergic rhinitis - a GA²LEN study (Bousquet et al, Int Arch Allergy Immunol 2010)
• Comparison of the efficacy and safety of bilastine 20 mg vs desloratadine 5 mg in seasonal allergic rhinitis patients (Bachert et al, Allergy 2009)
• Levocetirizine improves health-related quality of life and health status in persistent allergic rhinitis.(Walter Canonica G, et al, Respir Med. 2006)
• Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis. (Wahn U et al, JACI 2003)
• Mizolastine provides effective symptom relief in patients suffering from perennial allergic rhinitis: a double-blind, placebo-controlled study versus loratadine. (Frèche C, et al., Ann Allergy Asthma Immunol. 2002)
• Mizolastine therapy also has an effect on nasal blockade in perennial allergic rhinoconjunctivitis. RIPERAN Study Group. (Bachert C et al, Allergy 1998)

Acute rhinosinusitis

• Herbal drug BNO 1016 is safe and effective in the treatment of acute viral rhinosinusitis. (Jund R,et al, .Acta Otolaryngol. 2015)
• Dry extract of five herbal drugs for the treatment acute viral rhinosinusitis (Jund et al, Rhinology 2012).
• Treatment of acute rhinosinusitis with the preparation from Pelargonium sidoides EPs 7630: a randomized, double-blind, placebo-controlled trial (Bachert C, et al, Rhinology. 2009)
• Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo for the treatment of acute rhinosinusitis (Meltzer et al, JACI 2005)

Chronische rhinosinusitis

• Assessment of efficacy and safety of the herbal medicinal product BNO 1016 in chronic rhinosinusitis. (Palm J, et al, .Rhinology. 2017)
• Efficacy and safety of mometasone furoate nasal spray in the treatment of chronic rhinosinusitis (Mösges R et al, Adv Ther. 2011)
• The effect of topical amphotericin B on inflammatory markers in patients with chronic rhinosinusitis: a multicenter randomized controlled study (Ebbens et al, Laryngoscope 2009)

Neuspoliepen

• Reduced need for surgery in severe nasal polyposis with mepolizumab: Randomized trial. (Bachert C, et al, J Allergy Clin Immunol. 2017)
• Prospective open-label evaluation of long-term low-dose doxycycline for difficult-to-treat chronic rhinosinusitis with nasal polyps. (Pinto Bezerra Soter AC, et al,Rhinology. 2017)
• Alcohol hyper-responsiveness in chronic rhinosinusitis with nasal polyps. (De Schryver E, et al. Clin Exp Allergy. 2017)
• Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial. (Bachert C, et al, JAMA. 2016)
• Omalizumab, humanized monoclonal anti-IgE for the treatment of allergic and nonallergic patients with nasal polyps and asthma (Gevaert et al, JACI 2013)
• Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis.(Gevaert P et al, JACI 2011)
• Oral steroids and doxycycline: two different approaches to treat nasal polyps (Van Zele et al, JACI 2010)
• Effect of corticosteroids on wound healing after endoscopic sinus surgery (Jorissen M, and Bachert C, Rhinology. 2009)
• Pilot study using doxycycline-releasing stents to ameliorate postoperative healing quality after sinus surgery (Huvenne et al, Wound Repair Reg 2008).
• Reslizumab: Nasal IL-5 levels determine the response to anti-IL-5 treatment in patients with nasal polyps.(Gevaert P, et al, JACI 2006)