Lecture: “Monogenic defects in autoimmune deficiencies – lessons learned from lupus”

Prof. Dr. Alexandre Belot is an outstanding academic researcher and clinician in the field of immunology and pediatric rheumatology. He was trained both in Lyon and Paris in the unit of pediatric Immunology of Prof. Alain Fischer at Necker's Hospital. After a PhD in Immunology, he attended a post-doctoral position in genetics in Manchester in the group of Prof. Yanick Crow. Since 2013, he is the Head of the Pediatic Rheumatology Unit & the National Referee Centre for rare juvenile rheumatisms and systemic autoimmune diseases "RAISE" at the Pediatric Hospital "HFME" at the Hospices Civils de Lyon.

Involved in the national rare disease program, he co-chairs the national network on rare autoimmune and autoinflammatory diseases (FAI2R, www.fai2r.org) and is involved in the national research program on inflammatory diseases (www.imidiate.org). His research group inside the Lab "Innate Immunity in autoimmune and infectious diseases" headed by Dr. T. Walzer is dedicated to the molecular understanding of early-onset inflammatory diseases, with a special interest for monogenic lupus.

He is also running the educational program on pediatic rheumatology in France. He is the author of more than 150 publications in the field of pediatric rheumatology.